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have a digenetic daily life cycle, involving a motile, extracellular promastigote stage that parasitizes the alimentary tract of the sandfly vector and an immotile amastigote phase that survives and replicates in the phagolysosomes of mononuclear phagocytes [two,three]. Apart from humans, Major hosts of Leishmania, et al Loss of MAP3K7 sensitizes p